Assessment of Dietary Intake of Molybdenum in Relation to Tolerable Upper Intake Level

Determination of the tolerable upper intake level of leucine in acute dietary studies in young men.

BACKGROUND Leucine has been suggested to improve athletic performance. Therefore, the branched-chain amino acids (BCAAs), especially leucine, are popular as dietary supplements in strength-training athletes; however, the intake of leucine in excess of requirements raises concerns regarding adverse effects. Currently, the tolerable upper intake level (UL) for leucine is unknown. OBJECTIVE The ...

Opinion on the Tolerable Upper Intake Level of Biotin

Evaluation of dietary intake data using the tolerable upper intake levels.

We discuss the problem of assessing nutrient intake relative to the tolerable upper intake levels (UL) for the nutrient proposed by the Institute of Medicine and focus on 2 important topics: the estimation of usual nutrient intake distributions and the extent to which intakes above the UL can be considered risky. With the information that is currently available for most nutrients, it is not pos...

[Tolerable upper intake level on vitamins and minerals].

According to the safety assessments of all vitamins and minerals intake undertaken by the US Institute of Medicine's Food and Nutrition Board (FNB), UK MAFF Expert Group on Safety and European Scientific Committee on Food, we are reviewing that the rationale of making ULs (the risk of experiencing adverse effects, assessment for dosage and reaction and Uncertainty Factors); comparing ULs of mai...

Plasma molybdenum reflects dietary molybdenum intake.

The relationship between plasma molybdenum (Mo) and dietary intake has not been investigated in humans. We developed an isotope dilution method to determine molybdenum in 0.5 mL blood plasma by ICP-MS and conducted a study to determine the effect of dietary intake on plasma molybdenum. Twelve young men consumed a very low Mo diet (22 microg/day) for 24 days while confined to the WHNRC metabolic...